Nucleotica

Nanosensor Platform for Advanced DNA and RNA Analysis

Step beyond digital PCR with fast, portable, and precise nanosensor diagnostics.

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Technology

Our innovative technology harnesses the power of carbon nanotube sensors to detect DNA hybridisation with unparalleled sensitivity

How It Works

DNA probes are immobilised on the sensor surface, allowing them to bind complementary DNA or RNA sequences in a sample. This hybridisation induces measurable changes in the sensor’s electrical properties, enabling the detection of even trace amounts of target molecules.

What makes it unique

Unlike traditional PCR-based methods, our system eliminates the need for fluorescence detection, enzymatic reactions, or optical components. This makes it portable, robust, and free from the need for calibration.

Product

Powerful platform.
Device, Nanosensors, Software.

Device

Device. Portable, reliable, and fast.

Our compact device is optimized for rapid diagnostics in the lab or field. It’s vibration-resistant, calibration-free, and performs analysis in under 30 minutes.

Nanosensors

Nanosensors. Innovative for every sample.

Our carbon nanotube nanosensors use DNA probes for high sensitivity, enabling the detection of extremely low concentrations of target molecules. They resist inhibitors and work effectively with degraded DNA samples.

Software

Software. Intuitive and powerful analytical tools.

Our software simplifies data analysis. From SNP detection to liquid biopsy, it empowers clinicists and researches to make quick and optimal decisions.

Solutions

Applications
of Nucleotica Platform.

01
Cardiology.

Cardiology.

Using circulating DNA and SNP analysis, our technology helps detect cardiovascular risks earlier than ever before.
To Cardiology case
02
Oncology.

Oncology.

Empowering both pediatric and adult oncology, our platform excels in liquid biopsy analysis and mutation detection with unmatched sensitivity.
To Oncology case
03
Bacteriology.

Bacteriology.

Enabling rapid, field-ready detection of pathogens, our system accelerates interventions and improves outcomes in infectious disease management.
To Infectious diseases case
04
Virology.

Virology.

From RNA virus genomes to highly variable pathogens, our nanosensor platform adapts to the needs of virologists and researchers in real time.
To Virology case

Solutions for businesses

Custom expertise.
Delivering tailored Innovations with our technology

Custom assay development.

Design and manufacture of devices tailored to your specific requirements, including fully custom instruments and individual units.

Modification or customization of existing equipment to optimize your processes and enhance performance.

Nucleotica

We developed the high-precision device Nucleotica Sens 6

Scientific research and support.

Full-cycle project execution, including research design, assay development, and data analysis.

Advanced services such as PCR, NGS, and microbiome studies to meet your scientific needs.

Preparation of detailed reports, statistical analyses, and publication drafts to support your work.

Integration in labs and medical centers.

Helping B2B clients incorporate cutting-edge technologies into their existing infrastructure.

Providing training seminars and expert consultations tailored to your goals.

Nucleotica

Our platform is already assisting laboratories in their research.

Partnership

We welcome scientific and research partnerships

Scientific research centers.

Scientific research centers.

Collaborating on groundbreaking studies and technology development.

Providing expertise and resources to achieve mutual research goals.

Medical and biotech institutes.

Medical and biotech institutes.

Supporting research in diagnostics, treatment development, and bioinformatics.

Offering custom solutions for molecular biology, genomics, and microbiome studies.

Laboratories.

Laboratories.

Partnering with diagnostic and research labs to optimize workflows and implement advanced technologies.

Delivering tailored tools, reagents, and methodologies to enhance lab capabilities.

Other industry players.

Other industry players.

Engaging with pharmaceutical companies, healthcare providers, and startups to bring innovative ideas to life.

Co-developing solutions that meet the evolving needs of the medical and biotech industries.

Publications

Explore our groundbreaking research published in leading journals and presented at international conferences.

A single-molecule label-free identification of single-nucleotide colorectal-cancer-DNA polymorphism using impedance spectroscopy of self-redox-active decorated carbon nanotubes

Semiconductors, Vol. 54, no. 14, p. 1873–1876 (2020)

V.P. Egorova, H.V. Grushevskaya, A.S. Babenka, R.F. Chakukov, N.G. Krylova, I.V. Lipnevich, E.V. Vaskovtsev.

Nanopore-Penetration Sensing Effects for Target DNA Sequencing via Impedance Difference Between Organometallic-Complex-Decorated Carbon Nanotubes with Twisted Single-Stranded or Double-Stranded DNA

Advanced Nanomaterials for Detection of CBRN. NATO Science for Peace and Security Series A: Chemistry and Biology. / J. Bonca, S. Kruchinin (eds.) Springer, Dorchester, Chapter 17, p. 247-258 (2020)

A. S. Babenko, H. V. Grushevskaya, N. G. Krylova, I. V. Lipnevich, V. P. Egorova, R. F. Chakukov

Carbon nanotubes as a high-performance platform for target delivery of anticancer quinones

Current Pharmaceutical Design, Vol. 24 (43), p. 5207–5218 (2018)

H.V. Grushevskaya, N.G. Krylova

Contact us

Reach out to start your next innovation today.